Studs interviews blues singers Willie Dixon, Sunnyland Slim, and Willie Mae Big Mama Thornton about the blues. They discuss the blues festival in Chicago for which they are all in town for and name other musicians who will be performing. Sunnyland Slim talks about being on the road and the hard times. Thornton describes the blues as music made from life experiences.

Interviewing Willie Dixon and Memphis Slim at Aux Trois Mailletz while Studs was in France.

Studs interviews Willie Dixon and Koko Taylor about the blues. They discuss their song "Insane Asylum" and their work together. Dixon uses his song "Little Red Rooster" to help explain how the blues are created from life experiences. Taylor reflects on singers like Willie Dixon, Memphis Minnie, and others who influenced her desire to sing the blues. Taylor also discusses European audiences and blues influence there. The musical numbers are removed from this edited version of the original recording.

Sweet Honey In The Rock, an African American female vocal group, discusses their music. They talk to Studs and play folk/blues/traditional music.

Studs Terkel listens in on Evanston Township High Schools', soul choral group, "The Spirit of Soul" as they rehearse for an upcoming concert. Musical director, Avon Gillespie, describes how the vocal improvisation of "The Spirit of Soul" singers brings an on the spot sense of joy. This reflection of African Heritage through song closes the gap between Africa and American shores and teaches Black people that their heritage is real, alive, and strong!

Son House discusses his life and career as a preacher and blues musician. He talks about his family, his religious background as a preacher, and his recent comeback after disappearing from music scene in 1943. He performs several songs during the interview, which have been removed due to copyright.

Shel Silverstein discusses his books and children's literature, and art. Shel Silverstein discusses his contemporaries, art, and life experiences.

Sandra Lieb discusses the book "Mother of the Blues: A Study of Ma Rainey." Includes songs sung by Ma Rainey such as "Runaway Blues," "See See Rider," "Moonshine Blues," and "Oh, Papa Blues." Includes poem "Ma Rainey" by Sterling Brown. Includes "Oh, Daddy," by Ethel Waters. Includes "Young Woman's Blues" by Bessie Smith.

Interviewing singer, guitarist, and civil rights activist Josh White and blues singer Sam Gary about their blues and folk music.

The blues and jazz are topics covered by Ralph Ellison. Ellison himself started to play the trumpet at the age of seven. Ellison said for him, when hearing classical music, he then had to go and find classical literature.

Presenting Corky Siegel's chamber blues

Terkel presents a musical performance by Roy Dunn

Music performance by Oscar Brown, Jr.