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Jonathan Miller reminisces about his childhood in Regent Park, London and offers his opinion on philosophy and the changing English class structure with the loss of the Indian empire. His remake of "Alice in Wonderland" for BBC 1 is reviewed and he states he is most interested in the human imagination.
Dr. Richard Selzer, a surgeon, reads essays from his book, "Mortal Lesson: Notes on the Art of Surgery." Dr. Selzer recalls moments of his profession that stuck with him including the removal of a diabetic women's leg and the removal of a botfly larvae. He also takes a poetic look at the liver and the skin, including a story about Henry Moss. Dr. Selzer finishes his interview with a story about his first time witnessing an abortion. A comedy skit by Mike Nichols and Elaine May is also played.