Studs interviews Willie Dixon and Koko Taylor about the blues. They discuss their song "Insane Asylum" and their work together. Dixon uses his song "Little Red Rooster" to help explain how the blues are created from life experiences. Taylor reflects on singers like Willie Dixon, Memphis Minnie, and others who influenced her desire to sing the blues. Taylor also discusses European audiences and blues influence there. The musical numbers are removed from this edited version of the original recording.

The day before their concert performance at North Park College, the Shanghai Quartet was at the WFMT studios. Betty Bucchari explained her job was to search for great musicians that were not well-known. The Li brothers were destined to play the violins, as their parents were music teachers for 15 years.

Singer Harry Belafonte discusses Black music including spirituals and jazz and how it has contributed to American culture.

Recorded live on Chicago's South Side. Robeson is ill at the time of recording. Speakers: Earl Dickerson, Etta Moten Barnett, Judge Sidney Jones, J. Mayo "Ink" Williams, Joan Brown (possibly Abena Joan Brown), Charles Hamilton, Margaret Burroughs, [John Gray's sister], [Stevens?]

Big Bill Broonzy discusses the blues with Studs. Big Bill talks about getting ready for a European tour, his young life, and his life as a musician. The following performances have been removed for copyright reasons: "Ride Alberta, ride," "Going Down the road feeling bad," "House rent stomp," "The glory of love," "Plow hand," "I feel so good," and "Make my getaway."