Studs Terkel interviews blues singer song-writer Janis Joplin. This program discusses the following: Joplin's song "Turtle Blues"; Joplin's idols Bessie Smith and Lead Belly; Joplin's style of singing; Joplin's song writing; the blues; Joplin's interpretation of "Summertime"; and various renditions of the jazz song "Summertime". The following musical excerpts were presented: "Turtle Blues"; "Summertime" (interpreted by Janis Joplin); "Summertime" (interpreted by Mahalia Jackson); "Summertime" (interpreted by Billie Holiday); "Ball and Chain"; "Piece of My Heart"; and "Billie's Blues".

Discussing the book "The New Grove Dictionary of American Music". They talk about American music and musicians of all kinds and from different periods. Includes Charles Ive's song "At the River" sung by Cleo Laine in the middle of the program.

Helen Humes discusses her career and touring with Count Basie and his orchestra. John McDonough is present for the interview and contributes. Songs sung by Helen are played throughout the interview: "He May Be Your Man", "Song of the Wanderer", "If I Could Be with You for One Hour Tonight" (2 recordings- one from 1940 and one from 1977), "Unlucky Woman", "They Can't Take That Away From Me", "Today I Sing the Blues", and "They Raided the Joint". Music has been removed for copyright reasons.

Singer Harry Belafonte discusses Black music including spirituals and jazz and how it has contributed to American culture.

Recorded live on Chicago's South Side. Robeson is ill at the time of recording. Speakers: Earl Dickerson, Etta Moten Barnett, Judge Sidney Jones, J. Mayo "Ink" Williams, Joan Brown (possibly Abena Joan Brown), Charles Hamilton, Margaret Burroughs, [John Gray's sister], [Stevens?]

Using past recordings, Ella discusses how she works with children to help them find their rhythms using call and response music and percussion. She explains the West African and Latin music influences within her own music. Music played includes Jenkins' own music such as "Miss Mary Mack," "Tahboo," and "Where Has My Little Dog Gone?" She also plays song written by Carl Orff and performed by the Chorus of the Children's Opera Group, such s "Pat-a-Cake," and "Name-Calling." Untitled West African music is also played. Music has been removed due to copyright restrictions.

Edith Wilson talks about her singing and acting career in California and throughout the states. Songs have been removed due to copyright restrictions.

Dempsey Travis presents a jazz program and discusses the life, the music, and the community of Chicago jazz from before The Great Depression until World War II. Travis discusses 1920s-1930s Chicago for Black families including rent parties, breakfast dances, employment opportunities, union strikes, and jazz.

Terkel interviews Corky Siegel and the West End String Quartet. Corky Siegel and the West End String Quartet also performs during the broadcast. They also discuss the musical genre of chamber blues.

Terkel comments and presents the music of Chanticleer, an acapella ensemble, comprised of 12 all male voices. Chanticleer discusses the following: the group vocal composition; the groups history; various recordings; and their influences. Chanticleer performs the following songs live on air: "Benedicamus Domino", "If Ye Love Me", "O Sacrum Convivium", "Nude Descending a Staircase", "When I Fall in Love", "Jesus Met the Woman at the Well", and "Magnificat a 12".

Brownie McGhee and Sonny Terry discuss their careers as blues musicians and longtime collaborators. The close relationship between Terry and McGhee is apparent as they perform a number of original and traditional songs during the interview. Songs have been removed due to copyright.

Studs interviews Brother John Sellers about his career and other blues singers. Sellers explains that religion influenced his music as did performers like Mahalia Jackson, Big Bill Broonzy, and Muddy Waters. Studs reads some of the lyrics of blues song, "In the Evening." Sellers describes street singers and blind singers. He describes the music and style of Jackson and Broonzy and some of his own songs. Sellers performs "Talk About A Child" and "Sally Go Round the Sunshine" live on the program.

Bob Koester, record producer and owner of Delmark Records, the United State's oldest independent jazz and blues label, talks about jazz, blues, and bebop musicians.

Blind John Davis, Chicago blues pianist, discusses his time playing in Germany and at the Blue Note jazz club, chitlin' parties, growing up on the West side of Chicago. He also recalls meeting and working with musicians like Tampa Red and Big Bill Broonzy. Music has been removed from this recording for copyright reasons.