In the of first of many appearances on Studs' radio show, Oliver Sacks discusses his book "Awakenings" and recounts several patient profiles from his groundbreaking treatment application of L-DOPA to sufferers of Sleeping sickness and Parkinson's disease. They explore his work in the context of Studs' concept of Feeling Tone and Sacks tells of a remarkable scene with aphasic patients reacting to a speech of then President Ronald Reagan.

Edwin T. Buehrer, a Unitarian minister, discusses Unitarianism, his book "Changing Climate of Religion", and human problems. They also discuss humanity, religion, life on other planets, science, and the universe. Includes a clip of Arthur C. Clarke speaking about the universe and life on other planets. Includes a clip of a boy talking about who he thinks God is. Includes a clip of a boy talking about the fall of Rome.

John Cage discusses his music, life, influences, and career. Rebroadcast of an interview with John Cage to celebrate his life and what would have been soon his 80th birthday. Includes a clip of John Cage reading/ telling a story in 1969 to Studs Terkel.